Longevity & CellularApproved

SS-31 (Elamipretide)

FDA-approved (2025) mitochondrial-targeted antioxidant that restores ATP production by stabilizing cardiolipin in the inner mitochondrial membrane.

Also known as: Elamipretide, Bendavia, Forzinity

IntravenousSubcutaneous

Important: This content is for informational and research purposes only and is not intended for human or veterinary use. Consult your physician for health-related guidance and laboratory monitoring.

How It Works

Binds cardiolipin on inner mitochondrial membrane, stabilizing cristae structure and suppressing electron leakage. Enhances ATP production efficiency while reducing ROS generation.

Key Benefits

  • Restored mitochondrial ATP production
  • Reduced mitochondrial ROS
  • Improved cellular energy status
  • Stabilized mitochondrial cristae
  • Long-term safety in Barth syndrome (168 weeks)

Dosing Protocols

Beginner / Intermediate

Dose

500 mcg

Frequency

Once daily subcutaneous (AM)

Cycle Length

4-8 weeks

Notes

Reconstitute 5 mg vial with 1 ml BAC water; rotate injection sites

Advanced

Dose

1 mg

Frequency

Once daily subcutaneous (AM)

Cycle Length

8-12 weeks

Notes

Titrate from 500 mcg up to 1 mg daily after the first week if tolerated

Side Effects & Safety

Common Side Effects

  • Injection site reactions (20-40% SubQ)
  • Headache (mild-moderate)
  • Dizziness or nausea (rare)
  • No serious cardiovascular toxicity

Contraindications

  • Currently none formally listed
  • Theoretical: severe systemic infection

Stacking & Synergies

These compounds have complementary mechanisms and may enhance results when used together.

CoQ10PQQNAD+ precursorsL-CarnitineExercise

Key Takeaway

Restore your cellular powerhouse: SS-31 stabilizes mitochondria for restored energy and resilience.

Research Disclaimer: This content is for informational and research purposes only. It is not medical advice. These products are not approved by the FDA for human consumption. Consult a qualified healthcare provider before starting any new protocol. The information provided is based on preclinical research and anecdotal reports and has not been formally evaluated in randomized controlled trials.